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nilotinib will enhance the level or outcome of propafenone by influencing hepatic/intestinal enzyme CYP3A4 metabolism.nilotinib will raise the level or result of tucatinib by Other (see comment). Avoid or Use Alternate Drug. Coadministration of tucatinib (a CYP2C8 substrate) with a solid or reasonable CYP2C8 inhibitors will increase tucatinib plasm